منابع مشابه
Fertility Preservation in Gynecological Cancers
For cancers of reproductive system in women, fertility preservation is complex. Fertility is also affected by therapies, however prevention is possible. Radiotherapy affects gonads, uterus, and subsequent pregnancy outcomes in all ages. However, degree and damage depend on dose, irradiation field, and age at the time of exposure. Ovarian transposition is considered if ovarian involvement is unl...
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Gynecologic cancers are the unregulated growth of neoplastic cells that arise in the cervix, ovaries, fallopian tubes, uterus, vagina, and vulva. Although gynecologic cancers are characterized by different signs and symptoms, studies have shown that they share common risk factors, such as smoking, obesity, age, exposure to certain chemicals, infection with human immunodeficiency virus (HIV), an...
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BARD1 is required for protein stability and tumor suppressor functions of BRCA1, which depend on the ubiquitin ligase activity of the BRCA1-BARD1 heterodimer. The NH(2)-terminal RING domains of both proteins act as interaction modules and form a ubiquitin ligase, which has functions in DNA repair, cell cycle checkpoint regulation, and mitosis. Interestingly, up-regulated expression of truncated...
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Background and Objective: Each type of cancer has its own histopathological findings that determine the type of treatment regimen and the course of the disease. The present study aimed to histopathologically determine the types of gynecological cancers in patients admitted to Baqiyatallah Hospital over a nine-year period. Materials and Methods: This retrospective study was conducted based on h...
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ژورنال
عنوان ژورنال: Exploration of Targeted Anti-tumor Therapy
سال: 2021
ISSN: 2692-3114
DOI: 10.37349/etat.2021.00033